Klaus-Armin Nave Selected Research

Membrane Proteins (Integral Membrane Proteins)

11/2017	Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2.
1/2016	Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking.
10/2011	Misalignment of PLP/DM20 transmembrane domains determines protein misfolding in Pelizaeus-Merzbacher disease.

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Klaus-Armin Nave Research Topics

Disease

8	Pelizaeus-Merzbacher Disease 10/2019 - 04/2002
7	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 10/2020 - 02/2002
6	Hypoxia (Hypoxemia) 09/2023 - 05/2009
6	Demyelinating Diseases (Demyelinating Disease) 01/2023 - 01/2006
6	Schizophrenia (Dementia Praecox) 01/2021 - 07/2012
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 04/2005
5	Peripheral Nervous System Diseases (PNS Diseases) 10/2019 - 02/2002
4	Encephalitis (Encephalitis, Rasmussen) 12/2022 - 10/2019
4	Atrophy 12/2021 - 04/2005
4	Multiple Sclerosis 10/2021 - 08/2006
3	Alzheimer Disease (Alzheimer's Disease) 06/2023 - 07/2013
3	Inflammation (Inflammations) 12/2022 - 01/2019
3	Gliosis 12/2021 - 04/2014
3	Paraplegia (Spastic Paraplegia) 11/2020 - 11/2006
3	Disease Progression 01/2019 - 11/2006
2	Amyloid Plaque 06/2023 - 07/2013
2	Brain Injuries (Brain Injury) 02/2023 - 01/2021
2	Neuroinflammatory Diseases 01/2020 - 10/2013
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2020 - 01/2017
2	Seizures (Absence Seizure) 11/2018 - 08/2006
2	Hereditary Spastic Paraplegia 11/2017 - 01/2016
2	Fasciculation (Fasciculations) 01/2013 - 01/2003
2	Type 2B2 Charcot-Marie-Tooth disease 10/2009 - 10/2009
1	Tomaculous neuropathy 02/2024
1	Wounds and Injuries (Trauma) 06/2023
1	Genetic Predisposition to Disease (Genetic Predisposition) 02/2023
1	Autoimmune Diseases of the Nervous System 12/2022
1	Memory Disorders (Memory Loss) 12/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Insulin Resistance 01/2020
1	Psychotic Disorders (Schizoaffective Disorder) 10/2019
1	Anti-N-Methyl-D-Aspartate Receptor Encephalitis 10/2019
1	Catatonia 01/2019
1	Tooth Diseases 01/2018
1	Mental Disorders (Mental Disorder) 01/2018
1	Diabetic Neuropathies (Diabetic Neuropathy) 03/2017
1	Disease Susceptibility (Diathesis) 01/2017
1	Neuromyelitis Optica (Devic's Disease) 12/2016
1	Thymoma (Thymic Carcinoma) 04/2016
1	Parkinsonian Disorders (Parkinsonism) 01/2016
1	Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease) 01/2016

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 11/2017 - 04/2002
8	CholesterolIBA 10/2021 - 04/2002
6	Myelin ProteinsIBA 02/2024 - 04/2005
5	AutoantibodiesIBA 12/2022 - 12/2016
4	Erythropoietin FDA Link 09/2023 - 10/2007
4	Neuregulin-1 (Neuregulin 1)IBA 01/2021 - 08/2014
4	RNA (Ribonucleic Acid)IBA 01/2020 - 09/2008
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2022 - 10/2019
3	Membrane Proteins (Integral Membrane Proteins)IBA 11/2017 - 10/2011
3	LipidsIBA 01/2011 - 08/2003
2	Oxygen (Dioxygen)IBA 09/2023 - 01/2021
2	Amyloid (Amyloid Fibrils)IBA 06/2023 - 07/2013
2	AntigensIBA 02/2023 - 12/2022
2	NMDA receptor A1IBA 12/2022 - 12/2021
2	Diphtheria ToxinIBA 12/2021 - 01/2021
2	Peptides (Polypeptides)IBA 12/2021 - 07/2013
2	Messenger RNA (mRNA)IBA 03/2021 - 12/2014
2	Adenosine Triphosphate (ATP)IBA 11/2020 - 01/2017
2	Tamoxifen FDA LinkGeneric 10/2019 - 06/2012
2	Naltrexone (ReVia)FDA LinkGeneric 01/2019 - 12/2014
2	Sorbitol (Yal)FDA Link 01/2019 - 12/2014
2	Baclofen FDA LinkGeneric 01/2019 - 12/2014
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 02/2014
2	Prion ProteinsIBA 11/2011 - 03/2010
2	Myelin Proteolipid ProteinIBA 08/2009 - 04/2002
2	Progesterone FDA LinkGeneric 01/2007 - 12/2003
1	PotassiumIBA 01/2023
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022
1	Sirtuin 2IBA 01/2022
1	ParvalbuminsIBA 12/2021
1	tdTomatoIBA 03/2021
1	DesmosterolIBA 01/2021
1	Liver X ReceptorsIBA 01/2021
1	Recombinases (Recombinase)IBA 01/2021
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2020
1	Hormones (Hormone)IBA 01/2020
1	KetonesIBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	OvalbuminIBA 10/2019
1	Immunoglobulin G (IgG)IBA 10/2019
1	Dizocilpine Maleate (Dizocilpine)IBA 10/2019
1	Apolipoproteins E (ApoE)IBA 10/2019
1	NucleotidesIBA 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019
1	PLX5622IBA 01/2019
1	Potassium Channels (Potassium Channel)IBA 11/2018
1	Spironolactone (Aldactone)FDA LinkGeneric 10/2017
1	EpitopesIBA 01/2017
1	AutoantigensIBA 01/2017
1	Myelin Basic ProteinIBA 12/2016
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2016
1	Mitogen-Activated Protein KinasesIBA 04/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016
1	CurcuminIBA 08/2015

Therapy/Procedure

9	Therapeutics 10/2020 - 01/2007
2	Ketogenic Diet 10/2019 - 01/2019
1	Cognitive Training 09/2023